Esophageal adenocarcinoma after Nissen’s fundoplication for Barrett’s esophagus: report of a case
| Autor: | Kevin J. Monahan, Phillipa L. Youd, Peter Willson |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Esophageal Neoplasms medicine.medical_treatment Fundoplication Malignancy Nissen fundoplication Barrett Esophagus Surgical oncology medicine Humans Esophagus business.industry General surgery Reflux General Medicine Middle Aged medicine.disease humanities digestive system diseases Surgery medicine.anatomical_structure Barrett's esophagus GERD Adenocarcinoma Female business |
| Zdroj: | Surgery Today. 40:1173-1175 |
| ISSN: | 1436-2813 0941-1291 |
| DOI: | 10.1007/s00595-009-4221-4 |
| Popis: | It remains unclear whether surgical treatment of gastro-esophageal reflux disease (GERD) and Barrett's esophagus (BE) decreases the long-term risk of lower esophagus malignancy; yet, proposed reductions in Barrett's epithelial transformation have been used as a rationale for antireflux surgery. We report the case of a 63-year-old woman with a 40-year history of GERD, whose symptoms returned after a Nissen fundoplication. A gastroscopy done 3 years later revealed BE. Despite close surveillance, adenocarcinoma of the lower esophagus was diagnosed 8 years after the original surgery. Thus far, there is insufficient evidence to convince practitioners that surgery should be the first line of treatment to prevent malignant change in BE. Further well-standardized, prospective trials are required. Our case demonstrates that antireflux surgery in a patient with GERD and BE cannot be relied upon to prevent adenocarcinoma. |
| Databáze: | OpenAIRE |
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