BIOMATERIAL IMPLANTS IN BONE FRACTURES PRODUCED IN RATS FIBULAS

Autor: Diogo Yochizumi Oda, Thiago Cerizza Pinheiro, Marcelo Rodrigues da Cunha, Henrique Yassuhiro Shirane
Rok vydání: 2010
Předmět:
Zdroj: Revista Brasileira de Ortopedia
ISSN: 2255-4971
DOI: 10.1016/s2255-4971(15)30439-0
Popis: To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. Method: 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. Results: Little bone neoformation occurred inside the tubes filled with the biomaterials. There was more neoformation in the tubes with collagen. Conclusion: The biomaterials used demonstrated biocompatibility and osteoconductive capacity that was capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of rats.
Databáze: OpenAIRE