Group B streptococcus colonization in pregnant diabetic women
| Autor: | S Jenkins, L R Hearing, G. O. Del Valle, D Briones, E Ramos, F L Gaudier |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
medicine.medical_specialty Pregnancy in Diabetics medicine.disease_cause Sensitivity and Specificity Group B Streptococcus agalactiae Predictive Value of Tests Pregnancy Streptococcal Infections Diabetes mellitus medicine Humans Prospective Studies Risk factor Streptococcus Obstetrics business.industry Obstetrics and Gynecology Odds ratio medicine.disease Gestational diabetes Diabetes Gestational Logistic Models Carrier State Immunology Gestation Female business |
| Zdroj: | Obstetrics & Gynecology. 89:257-260 |
| ISSN: | 0029-7844 |
| DOI: | 10.1016/s0029-7844(96)00489-9 |
| Popis: | Objective To evaluate the influence of maternal diabetes on the risk of group B streptococcus colonization during pregnancy. Methods We prospectively analyzed data on 105 pregnant women with diabetes mellitus, both pregestational and gestational, and a control group of 300 pregnant women without carbohydrate intolerance. All had singleton gestations, negative tests for human immunodeficiency virus, and intact membranes at enrollment. Culture specimens for group B streptococcus were obtained from the lower vaginal walls and rectum. Two-tailed unpaired Student t test, Mann-Whitney U test, and χ 2 test were used as appropriate. Multiple logistic regression analyses were performed to evaluate the independent influence of maternal diabetes on the rate of group B streptococcus colonization. Results Compared to controls, diabetic women had a higher colonization rate (43.8 versus 22.7%, odds ratio [OR] 2.56, 95% confidence interval [CI] 1.6, 4.1). The prevalence of group B streptococcus colonization in pregestational diabetic women was 54.1% and in women with gestational diabetes it was 35.1% ( P = .05). Among women with pregestational diabetes, the prevalence of group B streptococcus colonization was 59.1% in class B and 50.0% in class C to R ( P = not significant). After we adjusted for maternal age, race, and obesity, diabetic women continued to be at increased risk of group B streptococcus colonization (OR 3.1, 95% CI 1.8, 5.2). Conclusion Carbohydrate intolerance appears to be an independent risk factor for group B streptococcus colonization during pregnancy. |
| Databáze: | OpenAIRE |
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