A retrospective analysis of biochemical and haematological parameters in patients with eating disorders
| Autor: | Robert Barron, Warren Ward, Shannon R. B. Ward, Leanne Barron, Faye M. Barron, Jeremy C. S. Johnson, Ingrid Wagner, Cameron J.B. Ward |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
050103 clinical psychology
medicine.medical_specialty Parameter lcsh:RC435-571 Population Retrospective Biochemical Reference interval 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Internal medicine lcsh:Psychiatry medicine Vitamin D and neurology 0501 psychology and cognitive sciences Haematological 030212 general & internal medicine Vitamin B12 education education.field_of_study Nutrition and Dietetics medicine.diagnostic_test Bulimia nervosa business.industry 05 social sciences Not Otherwise Specified medicine.disease Primary care Psychiatry and Mental health Eating disorders Anorexia nervosa (differential diagnoses) Physical therapy Liver function tests business General practice Research Article |
| Zdroj: | Journal of Eating Disorders, Vol 5, Iss 1, Pp 1-11 (2017) Journal of Eating Disorders |
| ISSN: | 2050-2974 |
| DOI: | 10.1186/s40337-017-0158-y |
| Popis: | Background The objective of the study was to determine whether levels of biochemical and haematological parameters in patients with eating disorders (EDs) varied from the general population. Whilst dietary restrictions can lead to nutritional deficiencies, specific abnormalities may be relevant to the diagnosis, pathogenesis and treatment of EDs. Methods With ethics approval and informed consent, a retrospective chart audit was conducted of 113 patients with EDs at a general practice in Brisbane, Australia. This was analysed first as a total group (TG) and then in 4 ED subgroups: Anorexia nervosa (AN), Bulimia nervosa (BN), ED Not Otherwise Specified (EDNOS), and AN/BN. Eighteen parameters were assessed at or near first presentation: cholesterol, folate, vitamin B12, magnesium, manganese, zinc, calcium, potassium, urate, sodium, albumin, phosphate, ferritin, vitamin D, white cell count, neutrophils, red cell count and platelets. Results were analysed using IBM SPSS 21 and Microsoft Excel 2013 by two-tailed, one-sample t-tests (TG and 4 subgroups) and chi-square tests (TG only) and compared to the population mean standards. Results for the TG and each subgroup individually were then compared with the known reference interval (RI). Results For the total sample, t-tests showed significant differences for all parameters (p |
| Databáze: | OpenAIRE |
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