Osteosclerotic and osteolytic manifestations of hyperparathyroidism in a case of Tc99m SestaMIBI positive parathyroid adenoma
Autor: | Kalpa Jyoti Das, Aditi Khurana Sehgal, Ravinder Singh Sethi, Ashish Jaiman |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Hyperparathyroidism
medicine.medical_specialty Pathology endocrine system diseases business.industry Brown tumor Case Report medicine.disease Skull Osteosclerosis medicine.anatomical_structure parathyroid adenoma methylene diphosphonate bone scan medicine Radiology Nuclear Medicine and imaging Subperiosteal bone resorption Radiology primary hyperparathyroism Differential diagnosis Tc99m SestaMIBI business osteosclerotic skull lesion Primary hyperparathyroidism Parathyroid adenoma |
Zdroj: | Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India |
ISSN: | 0974-0244 0972-3919 |
Popis: | Primary hyperparathyroidism is the first differential diagnosis when a patient presents with asymptomatic hypercalcemia. The symptoms of hyperparathyroidism can be as grave as skeletal, cardiovascular, and neuropsychological changes. Skeletal manifestations are relatively common, and patient may present with generalized or focal bone pains, fragility fractures, subperiosteal bone resorption, and osteolytic lesions like brown tumors and salt and pepper appearance of the skull. However, focal osteosclerotic lesions of the skull are rare findings in hyperparathyroidism. Only a few cases of associated osteosclerosis are reported in the literature. Here, we report a case of Tc99m SestaMIBI positive parathyroid adenoma with coexisting osteolytic and osteosclerotic skull lesions on Tc99m methylene diphosphonate bone scan. |
Databáze: | OpenAIRE |
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