The Impact of Sarcopenia in Patients with Peritoneal Surface Disease
| Autor: | Amanda Taylor-Gehman, Brianna Spencer, Eric W. Schaefer, Colette R. Pameijer, Aubrey Juris |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Sarcopenia Population Disease Muscle mass outcomes intraperitoneal chemotherapy Pathology and Forensic Medicine cytoreduction peritoneal surface disease Young Adult Antineoplastic Combined Chemotherapy Protocols medicine Humans In patient education Peritoneal Neoplasms Aged Retrospective Studies Aged 80 and over education.field_of_study business.industry Muscles Cancer General Medicine Cytoreduction Surgical Procedures Hyperthermia Induced Brief Research Report Middle Aged medicine.disease Combined Modality Therapy Surgery Society Journal Archive medicine.anatomical_structure Oncology muscle mass Abdomen Hyperthermic intraperitoneal chemotherapy Female business |
| Zdroj: | Pathology and Oncology Research |
| ISSN: | 1532-2807 1219-4956 |
| Popis: | Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is increasingly performed in patients with advanced cancer in the abdomen. This treatment prolongs survival for some patients but is known to have a substantial rate of complications. Choosing patients for this procedure can be difficult, and no clear guidelines exist. Muscle mass is a general measure of a patient’s wellness, meaning that patients with low muscle mass for their body weight tend to have more complications from treatment and overall do worse. We evaluated muscle mass prior to surgery in our Cytoreductive surgery/hyperthermic intraperitoneal chemotherapy population to assess how many patients have low muscle mass and the impact on outcomes, such as length of hospital stay, complications and survival. We find that about 25% of our patient population has low muscle mass, and low muscle mass is associated with a higher burden of cancer and shorter survival. We were able to evaluate muscle mass in a small number of patients after surgery, expecting to find decreased muscle mass in all the patients after a complex operation and long recovery. In fact, none of the patients had low muscle mass, including those who were low prior to surgery. |
| Databáze: | OpenAIRE |
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