Prediction of neonatal survival according to lung‐to‐head ratio in fetuses with right congenital diaphragmatic hernia (CDH): A multicentre study from the Latin American CDH Study Group registry

Autor: Walter Ventura, Alma Gámez-Varela, Jonahtan Luna-García, Saulo Molina-Giraldo, Hugo López-Briones, Néstor Pavón-Gómez, Adolfo Etchegaray, Rogelio Cruz-Martinez, M. Martinez-Rodriguez, Rosa Villalobos-Gómez, Enrique Gil-Guevara, Eréndira Chávez-González
Rok vydání: 2021
Předmět:
Zdroj: Prenatal Diagnosis. 42:357-363
ISSN: 1097-0223
0197-3851
DOI: 10.1002/pd.6070
Popis: OBJECTIVE To evaluate survival outcomes of fetuses with right sided congenital diaphragmatic hernia (CDH) treated in Latin American centres and to assess the utility of left lung area to predict neonatal survival. METHODS A retrospective cohort including isolated right sided CDH cases managed expectantly during pregnancy in six tertiary centers from five Latin American countries. The utility of the observed/expected lung-to-head ratio (O/E-LHR) in predicting neonatal survival was assessed, and the best cut-off to predict prognosis was automatically selected by decision tree analysis. RESULTS A total of 99 right sided CDH cases were recruited, 58 isolated fetuses were selected at a median gestational age of 26.2 weeks, showing an overall survival rate of 26.2%. A linear trend was observed between survival and the O/E-LHR, showing that at higher O/E-LHR, the greater probability of survival (r = 0.56, p
Databáze: OpenAIRE
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