Electron microscopic examination of the anterior lens capsule in a case of Alport’s syndrome
Autor: | Gamze Men, Mürvet Tuncel, Orhan Zilelioglu, Mehmet Citirik, Coşar Batman |
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Rok vydání: | 2007 |
Předmět: |
Adult
Male Visual acuity genetic structures medicine.medical_treatment Lens Capsule Crystalline Visual Acuity Nephritis Hereditary Intraocular lens Cataract Diagnosis Differential chemistry.chemical_compound Lens Implantation Intraocular Anterior lens capsule medicine Humans Capsulorhexis Lens capsule Phacoemulsification business.industry Retinal Anatomy eye diseases Anterior lenticonus Microscopy Electron Ophthalmology chemistry sense organs medicine.symptom business Optometry |
Zdroj: | Clinical and Experimental Optometry. 90:367-370 |
ISSN: | 1444-0938 0816-4622 |
DOI: | 10.1111/j.1444-0938.2007.00134.x |
Popis: | Purpose: To report a case of Alport’s syndrome and to present electronmicroscopic examination findings of the anterior lens capsule of this patient. Method: A 21-year-old man was referred for low visual acuity and retinal pigment epithelial changes in the left eye. The patient and his relatives underwent detailed ophthalmological examination, including electrophysiological testing. The patient also underwent electronmicroscopic examination of the anterior lens capsule. Results: His visual acuity was 6/18 OD and 6/15 OS. Anterior lenticonus and subcapsular opacities were observed in the left eye. Cataract extraction by phacoemulsification with intraocular lens implantation was performed for his poor visual performance. During the capsulorhexis, the remarkably thin and fragile anterior capsule was noted and removed. Ultrastructural analysis of the anterior lens capsule showed a thinner central zone compared with the periphery. Conclusions: The course of Alport’s syndrome can be ameliorated by early diagnosis. Therefore, the ophthalmological examination of a patient with anterior lenticonus must be combined with a detailed medical evaluation. Ultrastructural analysis of the lens capsule can support the diagnosis of Alport’s syndrome. |
Databáze: | OpenAIRE |
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