Association Between Psoriasis and Depression: A Traditional Review

Autor: Andrew Mekaiel, Bilal Haider Malik, Ayesha Masood, Nuaman A Danawar, Faryal Mustansir Sahi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Cureus
ISSN: 2168-8184
Popis: Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain. Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes.
Databáze: OpenAIRE