Pheochromocytoma in an African warthog (Phacochoerus aethiopicus)
| Autor: | Gayle C. Johnson, Gretchen Cole, WmKirk Suedmeyer |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Nasal cavity
Male Pathology medicine.medical_specialty Swine Diastole Adrenal Gland Neoplasms Pheochromocytoma Lumbar Fatal Outcome parasitic diseases Medicine Animals Medulla Swine Diseases General Veterinary biology business.industry Chromogranin A General Medicine medicine.disease biology.organism_classification Immunohistochemistry medicine.anatomical_structure Epinephrine Epistaxis Anesthesia biology.protein Animal Science and Zoology Phacochoerus aethiopicus business medicine.drug |
| Zdroj: | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 39(4) |
| ISSN: | 1042-7260 |
| Popis: | A 14-yr-old male African warthog (Phacochoerus aethiopicus) with a chronic history of intermittent unilateral epistaxis, degenerative osteoarthritis, and intermittent weakness in the distal lumbar trunk was evaluated to determine the source of epistaxis. No obvious cause was determined, and in light of severe osteoarthritis and a holosystolic cardiac murmur, the animal was euthanized. A tumor of the right adrenal gland involving the medulla was found at gross necropsy. Immunohistochemical staining of the tumor was positive for chromogranin and negative for neurofilament protein, which was diagnostic for pheochromocytoma. No lesions were observed in either nasal cavity. Systolic, diastolic, and mean arterial pressures measured at the time of immobilization were elevated when compared with another African warthog immobilized with a similar anesthetic regimen. Additionally, the warthog had pronounced serum norepinephrine dominance with a norepinephrine:epinephrine ratio of 10.0, compared with 0.36 from clinically normal warthogs. Practitioners should consider pheochromocytoma when evaluating warthogs or swine for epistaxis. |
| Databáze: | OpenAIRE |
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