The Pamela Study: Main Findings and Perspectives
| Autor: | Marco Volpe, Giuseppe Mancia, Roberto Sega, Guido Grassi, Michele Bombelli, Maria Peronio, Gianmaria Brambilla, Rita Facchetti, E. Toso, D. Fodri |
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| Přispěvatelé: | Bombelli, M, Toso, E, Peronio, M, Fodri, D, Volpe, M, Brambilla, G, Facchetti, R, Sega, R, Grassi, G, Mancia, G |
| Rok vydání: | 2013 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Ambulatory blood pressure Prognosi Population Blood Pressure White coat hypertension Context (language use) Epidemiology Internal Medicine Humans Medicine Intensive care medicine education education.field_of_study business.industry Blood Pressure Determination Prognosis medicine.disease Masked Hypertension Blood pressure Italy Hypertension Emergency medicine business Body mass index Human |
| Zdroj: | Current Hypertension Reports. 15:238-243 |
| ISSN: | 1534-3111 1522-6417 |
| DOI: | 10.1007/s11906-013-0348-1 |
| Popis: | PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) is an epidemiological study, originally designed to determine the normality of home and ambulatory blood pressure values. The study was performed on 3,200 subjects, aged 25 to 74 years, randomly selected from the general population of Monza (Milan, Italy). In the study context we performed clinical, home and ambulatory blood pressure measurements, echocardiographic assessment of cardiac structure and function as well as laboratory examinations (glucose and lipids). Personal and family histories were collected. The same procedures were repeated 10 years later. During a 12-year follow-up, the incident cardiovascular events were validated. Cardiovascular and all-cause fatal events were collected for a 16-year follow-up. This article will review the main results of the PAMELA study, with particular emphasis on (1) the prognostic value of the different blood pressure measurements, (2) the relationships between metabolic variables and blood pressure and (3) the clinical relevance and prognostic importance of left ventricular mass values and alterations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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