Stereoselective Cross-Coupling Reaction of 2,4-Diaryl-1,1-diboryl-1,3-butadienes: Stereocontrolled Approach to 1,3,4,6-Tetraarylated 1,3,5-Hexatrienes

Autor:	Tamejiro Hiyama, Masaki Shimizu, Michael Schelper, Katsuhiro Shimono
Rok vydání:	2007
Předmět:	chemistry.chemical_compound chemistry Stereochemistry Aryl Organic Chemistry Diastereomer chemistry.chemical_element Stereoselectivity General Medicine Medicinal chemistry Coupling reaction Palladium
Zdroj:	Synlett. 2007:1969-1971
ISSN:	1437-2096 0936-5214
Popis:	The boryl group CIS to the C(3)=C(4) group in 2,4-aryl-1,1-bis(pinacolatoboryl)-1,3-butadienes undergoes Pd-catalyzed cross-coupling reaction with aryl iodides stereoselectively at room temperature, giving rise to the corresponding boronates as a single diastereomer. Subsequent coupling of the boronates with alkenyl -iodides allows us to synthesize 1,3,4,6-tetraarylated 1,3,5-hexa-trienes stereoselectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb45ed7a3b9a90943ee0de1b48f528d4 https://doi.org/10.1055/s-2007-982567 Zobrazit plný text záznamu