Albumin-impregnated polyester vascular prosthesis for abdominal aortic surgery: An improvement?

Autor: Eric Epailly, Hélène Petit, Bernard Eisenmann, J. L. Pasquali, François Levy, Nabil Chakfe, Philippe Nicolini, J. G. Kretz
Rok vydání: 1996
Předmět:
Male
medicine.medical_treatment
Blood Loss
Surgical
Periprosthetic
Prosthesis
law.invention
Body Temperature
Albumin-impregnated
Postoperative Complications
Randomized controlled trial
law
Medicine
Aorta
Abdominal
Prospective Studies
Randomised controlled trial
Medicine(all)
biology
Abdominal aorta
Anastomosis
Surgical
Blood loss
Exudates and Transudates
Systemic Inflammatory Response Syndrome
C-Reactive Protein
Elective Surgical Procedures
Anesthesia
Female
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Blood vessel prosthesis
Surface Properties
Inflammatory reaction
Polyesters
Aortic Diseases
Polyester
Blood Sedimentation
Postoperative Hemorrhage
Prosthesis Design
medicine.artery
Albumins
Humans
Blood Transfusion
Elective surgery
Blood Coagulation
Aged
business.industry
C-reactive protein
Albumin
Abdominal aortic surgery
Surgery
biology.protein
business
Follow-Up Studies
Zdroj: European Journal of Vascular and Endovascular Surgery. 12(3):346-353
ISSN: 1078-5884
DOI: 10.1016/s1078-5884(96)80255-3
Popis: Aim: To compare the peroperative blood loss and the postoperative systemic inflammatory reaction in patients receiving either a Vasculour II Albumin pre-impregnated prosthesis (VA group, n = 32) or a preclotted Vasculour II prosthesis (V group, n = 33) for elective surgery of the abdominal aorta. Setting: University Hospital. Design: Prospective, randomised study. Methods: Peroperative blood loss was measured over two different periods: Phase I from the beginning of the operation to the completion of the proximal anastomosis, when blood loss cannot be related to the model of prosthesis implanted and phase Ii after the completion of the proximal anastomosis to the end of the operation. Postoperative blood loss was evaluated by the determination of the retroperitoneal drainage volume over a period of 2 days immediately following the operation. The presence of periprosthetic fluid was measured with echography at days 4, 9, 30 and 60. The postoperative systemic inflammatory reaction was evaluated by measuring the sedimentation rate and the C reactive protein levels daily from day 1 to day 9, and at days 14, 21, 28, 45, and 60, and by measuring the body temperature daily from day 1 to day 9. Results: No significant differences of peroperative blood loss were observed. The same proportion of patients (35%) in both groups received homologous transfusion. The mean number of units of homologous blood transfused per patient was respectively 0.77 and 0.91 for the VA and the V group. The retroperitoneal drainage volume and the percentage of patients with periprosthetic fluid did not differ significantly. No significant differences in systemic postoperative inflammatory reaction were observed. Conclusion: There were no benefits in using albumin-impregnated prosthesis as opposed to preclotted prosthesis in terms of peroperative and postoperative blood loss, or by looking at the incidence of homologous blood transfusion. However, the glutaraldehyde cross-linked albumin did not induce any systemic inflammatory reaction.
Databáze: OpenAIRE
Externí odkaz: