Programmed cell death in host-symbiont associations, viewed through the Gene Ontology
Autor: | Marcus C. Chibucos, Brett M. Tyler, Donghui Li, Michelle Gwinn-Giglio, Candace W Collmer, Magdalen Lindeberg, Trudy Torto-Alalibo |
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Rok vydání: | 2009 |
Předmět: |
0106 biological sciences
Microbiology (medical) Programmed cell death Apoptosis Review Biology 01 natural sciences Microbiology 03 medical and health sciences Terminology as Topic otorhinolaryngologic diseases Symbiosis Plant Diseases 030304 developmental biology Genetics 0303 health sciences Bacteria Gene ontology Host (biology) Fungi Oomycetes Vocabulary Controlled Host-Pathogen Interactions Viruses 010606 plant biology & botany |
Zdroj: | BMC Microbiology |
ISSN: | 1471-2180 |
Popis: | Manipulation of programmed cell death (PCD) is central to many host microbe interactions. Both plant and animal cells use PCD as a powerful weapon against biotrophic pathogens, including viruses, which draw their nutrition from living tissue. Thus, diverse biotrophic pathogens have evolved many mechanisms to suppress programmed cell death, and mutualistic and commensal microbes may employ similar mechanisms. Necrotrophic pathogens derive their nutrition from dead tissue, and many produce toxins specifically to trigger programmed cell death in their hosts. Hemibiotrophic pathogens manipulate PCD in a most exquisite way, suppressing PCD during the biotrophic phase and stimulating it during the necrotrophic phase. This mini-review will summarize the mechanisms that have evolved in diverse microbes and hosts for controlling PCD and the Gene Ontology terms developed by the Plant-Associated Microbe Gene Ontology (PAMGO) Consortium for describing those mechanisms. |
Databáze: | OpenAIRE |
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