Dietary flavanones and citrus fruits influence cytokines and thyroid transcription factor-1 in an HDM-induced chronic asthma murine model
| Autor: | Saeed Kolahian, Mohammadreza Vafa, Abolfazl Barzegari, Amir Ali Shahbazfar, Amin Sabri, Ebrahim Sakhinia, Ensiyeh Seyedrezazadeh, Khalil Ansarin |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Naringenin food.ingredient Thyroid Transcription Factor 1 Medicine (miscellaneous) Orange (colour) Grapefruit juice 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food medicine TX341-641 Food science Asthma House dust mite Orange juice Thyroid transcription factor-1 Nutrition and Dietetics biology Nutrition. Foods and food supply Hesperetin food and beverages medicine.disease biology.organism_classification 030104 developmental biology chemistry 030220 oncology & carcinogenesis Flavanones Cytokines Citrus fruit Food Science |
| Zdroj: | Journal of Functional Foods, Vol 26, Iss, Pp 709-718 (2016) |
| ISSN: | 1756-4646 |
| Popis: | The effects of hesperetin plus naringenin, orange juice and grapefruit juice on mRNA expression of TNF-α, TGF-β1 and TTF-1 in a house dust mite (HDM)-induced asthma animal model were investigated. Interventional mice exposed to HDM for 6 weeks received hesperetin plus naringenin, orange plus grapefruit juice, orange juice, grapefruit juice or water during the last 4 weeks, whereas non-asthmatic control mice consumed water. Lung tissue TNF-α and TGF-β1 expressions in supplemented groups were significantly reduced (p |
| Databáze: | OpenAIRE |
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