How the gut parasitome affects human health

Autor: Gianluca Ianiro, Andrea Iorio, Serena Porcari, Luca Masucci, Maurizio Sanguinetti, Carlo Federico Perno, Antonio Gasbarrini, Lorenza Putignani, Giovanni Cammarota
Rok vydání: 2021
Předmět:
Zdroj: Therapeutic advances in gastroenterology. 15
ISSN: 1756-283X
Popis: The human gut microbiome (GM) is a complex ecosystem that includes numerous prokaryotic and eukaryotic inhabitants. The composition of GM can influence an array of host physiological functions including immune development. Accumulating evidence suggest that several members of non-bacterial microbiota, including protozoa and helminths, that were earlier considered as pathogens, could have a commensal or beneficial relationship with the host. Here we examine the most recent data from omics studies on prokaryota-meiofauna-host interaction as well as the impact of gut parasitome on gut bacterial ecology and its role as ‘immunological driver’ in health and disease to glimpse new therapeutic perspectives.
Databáze: OpenAIRE