Effect of fenbendazole in water on pigs infected with Ascaris suum in finishing pigs under field conditions
| Autor: | Minna Haimi-Hakala, Toomas Orro, Mari Heinonen, Tapio Laurila, Claudio Oliviero, Elias Jukola, Brian Lassen |
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| Přispěvatelé: | Departments of Faculty of Veterinary Medicine, Production Animal Medicine, Mari Heinonen / Principal Investigator, Research Centre for Animal Welfare, Animal Reproduction Science, Teachers' Academy |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Veterinary medicine Swine Biology 413 Veterinary science Weight Gain Placebo Feces 03 medical and health sciences Animal science Liver rejection Milk spots medicine Animals Anthelmintic Parasite Egg Count Ascaris suum Ovum Anthelmintics Swine Diseases 2. Zero hunger Ascariasis General Veterinary Ascaris Water Fenbendazole General Medicine 030108 mycology & parasitology Animal husbandry biology.organism_classification 3. Good health Red Meat Liver Female Parasitology medicine.symptom Weight gain medicine.drug |
| Zdroj: | Veterinary Parasitology. 237:1-7 |
| ISSN: | 0304-4017 |
| DOI: | 10.1016/j.vetpar.2017.03.005 |
| Popis: | The husbandry of pigs for meat production is a constantly developing industry. Most studies on the effects of Ascaris suum infection in pigs and its prevention with anthelmintics are over a decade old. We examined the effect of 2.5 mg fenbendazole per kg bodyweight administered in drinking water for two consecutive days on A. suum infection 1 and 6 weeks after pigs arrived to fattening units. We hypothesised that the treatment would reduce the presence of A. suum-infections, improve the average daily weight gain of pigs, reduce the percentage of liver rejections in pens by 50% and increase the lean meat percentage at slaughter by 1%. The study included a placebo group (427 pigs) and a treatment group (420 pigs) spanning four different farms previously reporting ≥15% liver rejection. The treatment was given for 2 consecutive days 1 and 6 weeks after the pigs arrived to the fattening unit. Faecal samples were collected during weeks 1, 6 and 12 from all pigs and examined for A. suum eggs. Blood was collected during weeks 1 and 12 from a subgroup of the pigs and examined for anti-A. suum antibodies and clinical blood parameters. Data on liver rejection and lean meat percentage were collected post-mortem. The proportion of Ascaris seropositive pigs changed from 8.6% to 22.2% and 20.3% to 16.3% in the placebo and treatment group respectively. Fenbendazole reduced the presence of A. suum eggs in faeces the percentage of liver rejections by 69.8%. The treatment did not affect daily weight gain or lean meat percentage. Pigs with A. suum eggs in faeces at week 6 had a lower average daily weight gain of 61.8 g/day compared with pigs without parasite eggs. Fenbendazole treatment may be a useful option for farms struggling with persistent A. suum problems and demonstrate a beneficial effect on the weight gain of the animals shedding eggs in faeces and result in fewer condemned livers at slaughter. |
| Databáze: | OpenAIRE |
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