Knowledge Translation Strategy to Reduce the Use of Potentially Inappropriate Medications in Hospitalized Elderly Adults
| Autor: | Hélène Payette, Mitchell Levine, Modou Sene, Josée Bergeron, Louise Mallet, Geneviève Ricard, Serge Brazeau, Benoit Cossette, Luc Lanthier, Thomas Joly-Mischlich, Jean-François Ethier, Marie-Claude Rodrigue |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Psychological intervention Inappropriate Prescribing 030204 cardiovascular system & hematology Teaching hospital Translational Research Biomedical 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine Knowledge translation Intervention (counseling) medicine Humans 030212 general & internal medicine Elderly adults Hospitals Teaching Alert system Potentially Inappropriate Medication List Aged Aged 80 and over Gastrointestinal agent business.industry Potentially Inappropriate Medications Hospitalization Female Geriatrics and Gerontology business |
| Zdroj: | Journal of the American Geriatrics Society. 64:2487-2494 |
| ISSN: | 0002-8614 |
| Popis: | Objectives To evaluate the effect of a knowledge translation (KT) strategy to reduce potentially inappropriate medication (PIM) use in elderly inpatients in the hospital. Design Segmented regression analysis of an interrupted time series. Setting Teaching hospital. Participants Individuals aged 75 and older discharged from the hospital in 2013/14 (mean age 83.3, 54.5% female). Intervention The KT strategy comprises the distribution of educational materials, presentations by geriatricians, pharmacist–physician interventions based on alerts from a computerized alert system, and comprehensive geriatric assessments. Measurements Rate of PIM use (number of patient-days with use of at least one PIM/number of patient-days of hospitalization for individuals aged ≥75). Results For 8,622 patients with 14,071 admissions, a total of 145,061 patient-days were analyzed. One or more PIMs were prescribed on 28,776 (19.8%) patient-days; a higher rate was found for individuals aged 75 to 84 (24.0%) than for those aged 85 and older (14.4%) (P < .001), and in women (20.8%) than in men (18.6%) (P < .001). The drug classes most frequently accounting for the PIM were gastrointestinal agents (21%), antihistamines (18%), and antidepressants (17%). An absolute decrease of 3.5% (P < .001) of patient-days with at least one PIM was observed immediately after the intervention. Conclusion A KT strategy resulted in decreased use of PIM in elderly adults in the hospital. Additional interventions will be implemented to maintain or further reduce PIM use. |
| Databáze: | OpenAIRE |
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