Periodic Adhesive Fingers between Contacting Cells
| Autor: | Daniel Riveline, Peter Lenz, D. Gulino, Julien Brevier, M. Vallade, Hélène Delanoë-Ayari, M. Weidenhaupt, Jean-François Joanny |
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| Přispěvatelé: | Physico-Chimie-Curie (PCC), Centre National de la Recherche Scientifique (CNRS)-Institut Curie [Paris]-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Periodicity
Materials science Membrane Fluidity Kinetics General Physics and Astronomy Nanotechnology CHO Cells 01 natural sciences Membrane Fusion Models Biological Membrane tension Adherens junction 03 medical and health sciences Cricetulus Cricetinae 0103 physical sciences Cell Adhesion Animals Computer Simulation Symmetry breaking 010306 general physics 030304 developmental biology [PHYS]Physics [physics] 0303 health sciences Cadherin Adhesion Adherens Junctions Cadherins Symmetry (physics) body regions Actin Cytoskeleton Biophysics Adhesive |
| Zdroj: | Physical Review Letters Physical Review Letters, 2004, 93 (10), pp.108102. ⟨10.1103/PhysRevLett.93.108102⟩ |
| ISSN: | 0031-9007 1079-7114 |
| DOI: | 10.1103/PhysRevLett.93.108102⟩ |
| Popis: | We study in detail the properties of fingers, a particular type of cell-cell adhesive structures appearing in adherens junctions. These periodic patterns break the symmetry of cell-cell contacts. We show that finger formation is driven by cadherin interactions and actin growth. A theoretical model is introduced in which the growth of fingers is limited by membrane tension. The steady shape and formation kinetics of fingers are experimentally measured and compared with the theoretical predictions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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