Oral Microbes, Biofilms and Their Role in Periodontal and Peri-Implant Diseases

Autor: Jérôme F Lasserre, Michel C. Brecx, Selena Toma
Rok vydání: 2018
Předmět:
Zdroj: Materials
Materials, Vol 11, Iss 10, p 1802 (2018)
ISSN: 1996-1944
DOI: 10.3390/ma11101802
Popis: Despite many discoveries over the past 20 years regarding the etio-pathogenesis of periodontal and peri-implant diseases, as well as significant advances in our understanding of microbial biofilms, the incidence of these pathologies still continues to rise. This review presents a general overview of the main protagonists and phenomena involved in oral health and disease. A special emphasis on the role of certain keystone pathogens in periodontitis and peri-implantitis is underlined. Their capacity to bring a dysregulation of the homeostasis with their host and the microbial biofilm lifestyle are also discussed. Finally, the current treatment principles of periodontitis and peri-implantitis are presented and their limits exposed. This leads to realize that new strategies must be developed and studied to overcome the shortcomings of existing approaches.
Databáze: OpenAIRE
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