Neurological manifestations of scrub typhus in adults
| Autor: | Seema Sharma, Abhinav Rana, Sanjay K Mahajan, Balbir S Verma, Ashok Sharma, A. B. Sharma |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Orientia tsutsugamushi 030231 tropical medicine India Enzyme-Linked Immunosorbent Assay Neuroimaging Scrub typhus Sensitivity and Specificity 03 medical and health sciences Young Adult 0302 clinical medicine Cerebrospinal fluid Seizures medicine Humans Young adult Aged Aged 80 and over biology business.industry Public Health Environmental and Occupational Health Meningoencephalitis Middle Aged medicine.disease biology.organism_classification Magnetic Resonance Imaging Surgery Neuroleptic malignant syndrome Infectious Diseases Acute Transverse Myelitis Scrub Typhus Female business 030217 neurology & neurosurgery Typhus |
| Zdroj: | Tropical doctor. 47(1) |
| ISSN: | 1758-1133 |
| Popis: | In order to study the neurological manifestations in adult patients suffering from scrub typhus, 323 patients aged over 18 years, admitted with a positive diagnosis, were screened for neurological dysfunction; 37 patients with symptoms and/or signs suggestive of neurological dysfunction were included in the study. Of these, 31 (84%) patients had altered sensorium, four (11%) had cerebellitis, one (2%) patient had acute transverse myelitis and one (2%) had bilateral papilloedema without focal neurological deficit. Of the 31 patients with altered sensorium, 15 (40%) had meningoencephalitis, three (8%) had seizures, two (5%) had cerebral haemorrhages, one (2%) had a presentation likened to neuroleptic malignant syndrome (NMS) and one (2%) had a 6th nerve palsy with inflammation of the right cavernous sinus. Cerebrospinal fluid (CSF) analysis was abnormal in 23 patients (raised lymphocytes in 68%, raised protein in 80%). All patients improved with anti-rickettsial therapy. |
| Databáze: | OpenAIRE |
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