ArteFill® Permanent Injectable for Soft Tissue Augmentation: II. Indications and Applications
| Autor: | Gottfried Lemperle, Neil S. Sadick, Terry R. Knapp, Stefan M. Lemperle |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Bovine collagen Development period business.industry Soft tissue ArteFill Plastic Surgery Surgery Microsphere Plastic surgery Patient satisfaction Wrinkle treatment Otorhinolaryngology Permanent filler Artefill medicine Medicine & Public Health Soft tissue augmentation Original Article medicine.symptom business Dermal filler Wrinkle |
| Zdroj: | Lemperle, Gottfried; Sadick, Neil S.; Knapp, Terry R.; & Lemperle, Stefan M.(2010). ArteFill® Permanent Injectable for Soft Tissue Augmentation: II. Indications and Applications. Aesthetic Plastic Surgery, 34(3), pp 273-286. doi: 10.1007/s00266-009-9414-0. Retrieved from: http://www.escholarship.org/uc/item/4s59v3pv Aesthetic Plastic Surgery |
| DOI: | 10.1007/s00266-009-9414-0. |
| Popis: | Patients ask for procedures with long-lasting effects. ArteFill is the first permanent injectable approved in 2006 by the FDA for nasolabial folds. It consists of cleaned microspheres of polymethylmethacrylate (PMMA) suspended in bovine collagen. Over the development period of 20 years most of its side effects have been eliminated to achieve the same safety standard as today’s hyaluronic acid products. A 5-year follow-up study in U.S. clinical trial patients has shown the same wrinkle improvement as seen at 6 months. Long-term follow-up in European Artecoll patients has shown successful wrinkle correction lasting up to 15 years. A wide variety of off-label indications and applications have been developed that help the physician meet the individual needs of his/her patients. Serious complications after ArteFill injections, such as granuloma formation, have not been reported due to the reduction of PMMA microspheres smaller than 20 μm to less than 1% “by the number.” Minor technique-related side effects, however, may occur during the initial learning curve. Patient and physician satisfaction with ArteFill has been shown to be greater than 90%. |
| Databáze: | OpenAIRE |
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