Non-covalent stabilization of a β-hairpin peptide into liposomes
Autor: | Jeffrey G. Linhardt, Jan C. M. van Hest, Dennis W. P. M. Löwik, P. J. Hans M. Adams |
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Rok vydání: | 2003 |
Předmět: |
Models
Molecular chemistry.chemical_classification Oligopeptide Liposome Chemistry Circular Dichroism Non covalent Plasmodium falciparum Organic Chemistry Protozoan Proteins Peptide Biochemistry Combinatorial chemistry Protein Structure Secondary Random coil Liposomes Phosphatidylcholines Pressure Animals Organic chemistry Amino Acid Sequence Physical and Theoretical Chemistry Oligopeptides |
Zdroj: | Org. Biomol. Chem.. 1:1827-1829 |
ISSN: | 1477-0539 1477-0520 |
Popis: | An oligopeptide modified on both the N- and C-termini with hydrophobic moieties was prepared on a solid phase and anchored into a liposome, stabilizing the fold of the peptide into a beta-hairpin, which would otherwise be a random coil. |
Databáze: | OpenAIRE |
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