Group G Chromosomes and the Susceptibility of Cells of Human Origin to Coxsackie B Viruses

Autor:	G. P. Sovjetova, Amchenkova Am, Ya. E. Khesin
Rok vydání:	1974
Předmět:	Chromosome Aberrations Immunity Cellular viruses Cell Karyotype Biology medicine.disease_cause Virology Virus Cell Line medicine.anatomical_structure Leukemia Myeloid Cell culture Karyotyping Chromosomes Human 21-22 and Y medicine Humans Enterovirus Alkaline phosphatase Gene Intracellular
Zdroj:	Journal of General Virology. 23:17-22
ISSN:	1465-2099 0022-1317
DOI:	10.1099/0022-1317-23-1-17
Popis:	Summary Comparative karyological studies have been made on the J-96 line of human leukaemic cells, which are susceptible to enteroviruses, and on cell strains derived from this line which are persistently infected with Coxsackie B5 virus or free from infective virus but possessing high specific resistance to Coxsackie B3 or B5 viruses. It was shown that the karyotypes of these cell strains were characterized by reduced numbers of small acrocentric chromosomes of group G. It is suggested that group G chromosomes in cells of human origin incorporate genes which control alkaline phosphatase activity and the production of specific substances essential to adsorption and intracellular development of Coxsackie B viruses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae15f7954e42f9e628239cc7b7951af https://doi.org/10.1099/0022-1317-23-1-17 Zobrazit plný text záznamu