Telmisartan-induced sprue-like enteropathy: a case report
| Autor: | Lidia Montenegro, Teresa Acin, Natalia Alzueta, Javier Garjón, Lorea Sanz, Carmen Fontela, Amaya Echeverria |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Abdominal pain
medicine.medical_specialty Case Report 030226 pharmacology & pharmacy Gastroenterology Asymptomatic Sprue 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Enteropathy Telmisartan 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics Adverse effect Antihypertensive Agents Aged 80 and over business.industry medicine.disease Discontinuation Celiac Disease Hypertension Female medicine.symptom Olmesartan business Follow-Up Studies medicine.drug |
| Zdroj: | Eur J Hosp Pharm |
| ISSN: | 2047-9964 2047-9956 |
| DOI: | 10.1136/ejhpharm-2018-001669 |
| Popis: | A possible case of sprue-like enteropathy (SLE) induced by the use of telmisartan is reported. Telmisartan is an angiotensin-receptor II blocker (type 1) used for the treatment of hypertension. Several cases of SLE associated with olmesartan and other drugs of the same group have been reported. In all cases, SLE resolved following therapy withdrawal. We describe the case of an 80-year-old woman who presented with diarrhoea and abdominal pain. In the past 5 years she had been treated with telmisartan 40 mg once a day for hypertension, so we hypothesised that symptoms might be caused by telmisartan. After treatment discontinuation, diarrhoea disappeared. Three causality algorithms were applied and revealed a possible or likely causal relationship. At present, the patient remains asymptomatic. There is a causal relationship between the use of telmisartan and SLE. This association should be taken into account by physicians when prescribing and reviewing drug therapies. |
| Databáze: | OpenAIRE |
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