CT angiography-based collateral flow and time to reperfusion are strong predictors of outcome in endovascular treatment of patients with stroke

Autor: Paolo Stanzione, Roberto Gandini, Jacopo M. Legramante, Valentina Saia, Giacomo Koch, Domenico Samà, Salvatore Mangiafico, Roberto Floris, Enrico Pampana, Vittoria Carla D'Agostino, Fabrizio Sallustio, Daniel Konda, Caterina Motta, Angela Giordano, Marina Diomedi, Silvia Pizzuto
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
medicine.medical_specialty
Time Factors
Computed Tomography Angiography
CT Angiography
Stroke
Thrombectomy
Aged
Brain Ischemia
Cerebral Angiography
Collateral Circulation
Computed Tomography Angiography
Endovascular Procedures
Reperfusion
Time Factors
Treatment Outcome
Collateral Circulation
030218 nuclear medicine & medical imaging
NO
Brain Ischemia
Brain ischemia
03 medical and health sciences
0302 clinical medicine
Settore MED/36 - Diagnostica per Immagini e Radioterapia
Predictive Value of Tests
medicine
Humans
CT Angiography
Stroke
Thrombectomy
Computed tomography angiography
Aged
medicine.diagnostic_test
business.industry
Penumbra
Endovascular Procedures
General Medicine
Middle Aged
medicine.disease
Collateral circulation
Cerebral Angiography
Treatment Outcome
Predictive value of tests
Angiography
Reperfusion
Female
Surgery
Settore MED/26 - Neurologia
Neurology (clinical)
Radiology
business
030217 neurology & neurosurgery
Cerebral angiography
Popis: BackgroundCollateral flow (CF) is an effective predictor of outcome in acute ischemic stroke (AIS) with potential to sustain the ischemic penumbra. However, the clinical prognostic value of CF in patients with AIS undergoing mechanical thrombectomy has not been clearly established. We evaluated the relationship of CF with clinical outcomes in patients with large artery anterior circulation AIS treated with mechanical thrombectomy.MethodsBaseline collaterals of patients with AIS (n=135) undergoing mechanical thrombectomy were independently evaluated by CT angiography (CTA) and conventional angiography and dichotomized into poor and good CF. Multivariable analyses were performed to evaluate the predictive effect of CF on outcome and the effect of time to reperfusion on outcome based on adequacy of the collaterals.ResultsEvaluation of CF was consistent by both CTA and conventional angiography (pConclusionsCTA is a valid tool for assessing the ability of CF to predict clinical outcome in patients with AIS treated with mechanical thrombectomy. Limiting time to reperfusion is of definite value in patients with good collaterals and also to some extent in those with poor collaterals.
Databáze: OpenAIRE
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