Isolation of human immunodeficiency virus (HIV) from plasma during primary HIV infection
| Autor: | Lars Moberg, Birgitta Åsjö, Jan Albert, Knut Lidman, Gunnel Nyström, Eva Maria Fenyö, Madeleine von Sydow, A. Sönnerborg, Hans Gaines, Bertil Christensson, Pehr Olov Pehrson, Francesca Chiodi |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
Isolation (health care) Human immunodeficiency virus (HIV) Viremia HIV Antibodies Antibodies Viral medicine.disease_cause Peripheral blood mononuclear cell Virus Plasma Cerebrospinal fluid Immune system Virology medicine Humans Cerebrospinal Fluid Acquired Immunodeficiency Syndrome business.industry HIV virus diseases medicine.disease Infectious Diseases Carrier State Immunology Leukocytes Mononuclear business Asymptomatic carrier |
| Zdroj: | Journal of Medical Virology. 23:67-73 |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.1890230108 |
| Popis: | Human immunodeficiency virus (HIV) has been isolated from plasma in 6 of 7 patients showing clinical symptoms of a primary HIV infection. Parallel cultures from peripheral blood mononuclear cells (PBMC) yielded virus in 5 patients. In one case, virus could only be isolated from the cerebrospinal fluid but not from peripheral blood. Detectable viremia was transient and preceded the appearance of HIV specific antibodies. After cessation of acute symptoms, the frequency of HIV isolations was similar to that of asymptomatic carriers (23 and 26%, respectively). The role of the immune response in terminating detectable viremia remains to be established. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text