Supplementation by thylakoids to a high carbohydrate meal decreases feelings of hunger, elevates CCK levels and prevents postprandial hypoglycaemia in overweight women
| Autor: | Eva-Lena Stenblom, Maria Håkansson, Caroline Montelius, Karolina Östbring, Charlotte Erlanson-Albertsson, Jens F. Rehfeld, Sofia Nilsson |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Blood Glucose Meal supplement medicine.medical_specialty Time Factors Hunger medicine.medical_treatment Blood lipids Satiation Overweight Satiety Response Thylakoids Surveys and Questionnaires Internal medicine Dietary Carbohydrates medicine Humans Insulin Single-Blind Method Psychology(all) General Psychology Aged Cholecystokinin Meal Nutrition and Dietetics Tumor Necrosis Factor-alpha business.industry digestive oral and skin physiology food and beverages Middle Aged Carbohydrate Postprandial Period Ghrelin Hypoglycemia Diet Satiety Glucose Endocrinology Postprandial Dietary Supplements Female medicine.symptom business |
| Zdroj: | Appetite; 68, pp 118-123 (2013) |
| ISSN: | 0195-6663 1095-8304 |
| DOI: | 10.1016/j.appet.2013.04.022 |
| Popis: | Thylakoids are chlorophyll-containing membranes in chloroplasts that have been isolated from green leaves. It has been previously shown that thylakoids supplemented with a high-fat meal can affect cholecystokinin (CCK), ghrelin, insulin and blood lipids in humans, and can act to suppress food intake and prevent body weight gain in rodents. This study investigates the addition of thylakoids to a high carbohydrate meal and its effects upon hunger motivation and fullness, and the levels of glucose, insulin, CCK, ghrelin and tumour necrosis factor (TNF)-alpha in overweight women. Twenty moderately overweight female subjects received test meals on three different occasions; two thylakoid enriched and one control, separated by 1week. The test meals consisted of a high carbohydrate Swedish breakfast, with or without addition of thylakoids. Blood samples and VAS-questionnaires were evaluated over a 4-h period. Addition of thylakoids suppressed hunger motivation and increased secretion of CCK from 180min, and prevented postprandial hypoglycaemia from 90min following food intake. These effects indicate that thylakoids may intensify signals of satiety. This study therefore suggests that the dietary addition of thylakoids could aid efforts to reduce food intake and prevent compensational eating later in the day, which may help to reduce body weight over time. |
| Databáze: | OpenAIRE |
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