Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function
| Autor: | Lee Gerdes, Sean L. Simpson, Catherine L. Tegeler, Hossam A. Shaltout, Sung W. Lee, Charles H. Tegeler |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Autonomic function
medicine.medical_specialty insomnia 03 medical and health sciences stress 0302 clinical medicine Physical medicine and rehabilitation Neurotechnology law enforcement Medicine Autonomic dysregulation Heart rate variability 030212 general & internal medicine lcsh:R5-920 business.industry lcsh:Public aspects of medicine Pilot trial Traumatic stress Law enforcement heart rate variability lcsh:RA1-1270 General Medicine HIRREM Original Article neurotechnology business lcsh:Medicine (General) Closed loop 030217 neurology & neurosurgery |
| Zdroj: | Global Advances in Health and Medicine Global Advances in Health and Medicine, Vol 9 (2020) |
| ISSN: | 2164-9561 2164-957X |
| Popis: | Background Law enforcement officers have decreased life expectancy, attributed to work-related exposure to traumatic stress and circadian disruption. Autonomic dysregulation is reported with traumatic stress and chronic insomnia. Objective We explore potential benefits for reduced symptoms related to stress and insomnia and improved autonomic function associated with open label use of high-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), in a cohort of sworn law enforcement personnel. Methods Closed-loop noninvasive therapies utilizing real-time monitoring offer a patient-centric approach for brain-based intervention. HIRREM® is a noninvasive, closed-loop, allostatic, neurotechnology that echoes specific brain frequencies in real time as audible tones to support self-optimization of brain rhythms. Self-report symptom inventories done before and after HIRREM included insomnia (ISI), depression (CES-D), traumatic stress (PCL-C), anxiety (GAD-7), perceived stress (PSS), and quality of life (EQ-5D). Ten-minute recordings of heart rate and blood pressure allowed analysis of baroreflex sensitivity (BRS) and heart rate variability (HRV). Results Fifteen participants (1 female), mean (SD) age 45.7 (5.6), received 12.2 (2.7) HIRREM sessions, over 7.9 in-office days. Data were collected at baseline, and at 22.8 (9.2), and 67.2 (14.1) days after intervention. All symptom inventories improved significantly ( P Conclusion These pilot data provide the first report of significant symptom reductions, and associated improvement in measures of autonomic cardiovascular regulation, with the use of HIRREM in a cohort of law enforcement personnel. Randomized clinical trials are warranted. |
| Databáze: | OpenAIRE |
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