Could human cold adaptation decrease the risk of cardiovascular disease?
| Autor: | J. Rychlikova, I. Kralova Lesna, Stanislav Vybíral, L. Vavrova |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Thyroid Hormones medicine.medical_specialty GPX1 Homocysteine Physiology Glutathione reductase Biochemistry Antioxidants chemistry.chemical_compound Internal medicine medicine Humans Cells Cultured Swimming biology Cholesterol Paraoxonase Glutathione Middle Aged Atherosclerosis Lipid Metabolism Adaptation Physiological PON1 Hormones Cold Temperature Oxidative Stress Zinc Endocrinology chemistry Cardiovascular Diseases biology.protein Apolipoprotein A1 General Agricultural and Biological Sciences Developmental Biology |
| Zdroj: | Journal of Thermal Biology. 52:192-198 |
| ISSN: | 0306-4565 |
| DOI: | 10.1016/j.jtherbio.2015.07.007 |
| Popis: | The impact of repeated exposure to cold and cold adaptation on human cardiovascular health is not fully understood. The aim of the study was to determine the effect of cold adaptation on cardiovascular risk factors, thyroid hormones and the capacity of humans to reset the damaging effect of oxidative stress. Ten well cold-adapted winter swimmers (CA) and 16 non-adapted controls (CON) were enroled in this experiment to test whether cold adaptation could influence the parameters of lipoprotein metabolism, cholesterol efflux capacity (CEC), homocysteine, thyroid hormones, antioxidant defence markers (reduced glutathione (GSH), glutathione peroxidase 1 (GPX1), glutathione reductase (GR), catalase (CAT) and paraoxonase 1 (PON1)) and oxidative stress markers (concentration of conjugated dienes (CD)). A decreased apolipoprotein B/apolipoprotein A1 (ApoB/ApoA1) ratio was found in the CA group (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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