Intraductal carcinoma. Long-term follow-up after treatment by biopsy alone
Autor: | William L. Betsill, Guy F. Robbins, Philip H. Lieberman, Paul Peter Rosen |
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Rok vydání: | 1978 |
Předmět: |
Adult
medicine.medical_specialty Time Factors Long term follow up Biopsy medicine.medical_treatment Breast Neoplasms Metastatic carcinoma Carcinoma medicine Humans Neoplasm Metastasis medicine.diagnostic_test business.industry General surgery Follow up studies General Medicine Middle Aged medicine.disease Carcinoma Intraductal Noninfiltrating Female Radiology business Carcinoma in Situ After treatment Mastectomy Follow-Up Studies |
Zdroj: | JAMA: The Journal of the American Medical Association. 239:1863-1867 |
ISSN: | 1538-3598 0098-7484 |
Popis: | A follow-up period averaging 21.6 years was obtained for patients with low-grade papillary intraductal carcinoma initially treated only by biopsy between 1940 and 1950. Subsequent carcinoma was diagnosed in the same breast in seven of the ten patients after an average interval of 9.7 years. Six of the seven subsequent carcinomas were invasive. Two of the patients died of metastatic carcinoma and two were known to be alive with metastases when last contacted. Three patients were without carcinoma following mastectomy. When these results were combined with the few reports available in the literature, it appeared that at least 39% of patients with intraductal carcinoma treated by biopsy alone subsequently had clinically evident carcinoma, invariably in the same breast, with an average latent period of about ten years. This was undoubtedly a result of the multicentric nature of the disease in many patients. ( JAMA 239:1863-1867, 1978) |
Databáze: | OpenAIRE |
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