Recent developments in liposomal drug delivery systems for the treatment of retinal diseases
| Autor: | Anne Zebitz Eriksen, Andrew J. Urquhart |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Phospholipid vesicles Bioinformatics Retina 03 medical and health sciences chemistry.chemical_compound Drug Delivery Systems 0302 clinical medicine Retinal Diseases Drug Discovery medicine Animals Humans Disease treatment Pharmacology Liposome Blindness business.industry Retinal medicine.disease 030104 developmental biology medicine.anatomical_structure Pharmaceutical Preparations chemistry 030220 oncology & carcinogenesis Liposomes Drug delivery Nanoparticles business |
| Zdroj: | Drug Discovery Today. 24:1660-1668 |
| ISSN: | 1359-6446 |
| Popis: | Diseases of the retina cause vision loss and blindness, which have a profound impact on an individual's quality of life. The number of therapies available to treat retinal diseases is limited. Nanoparticle (NP)-based medicines represent one strategy to expand both the number of available therapies and the range of retinal diseases treated. Liposomes, phospholipid vesicles that frequently contain cholesterol and/or modified surface chemistries, have already had minor success in retinal disease treatment and hold significant promise. Here, we provide a snapshot of recent research developments in liposomal drug delivery systems for retinal diseases and discuss the challenges associated with liposomal systems in the context of recent developments. |
| Databáze: | OpenAIRE |
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