Depression in girls with obesity and polycystic ovary syndrome and/or type 2 diabetes
| Autor: | Lauren B. Shomaker, Anya Taylor, Julia Hudnut-Beumler, Lauren D. Gulley, Cameron Severn, Kristen J. Nadeau, Laura Pyle, Philip Zeitler, Natalie Abramson, Megan M. Kelsey, Stacey L. Simon, Melanie Cree-Green, Jessie Benson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty endocrine system diseases Adolescent Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Type 2 diabetes Article 03 medical and health sciences 0302 clinical medicine Endocrinology Surveys and Questionnaires Internal Medicine medicine Humans 030212 general & internal medicine Obesity Child Depression (differential diagnoses) hirsutism Acne Retrospective Studies Psychiatric Status Rating Scales Depressive Disorder business.industry nutritional and metabolic diseases General Medicine medicine.disease Prognosis Polycystic ovary female genital diseases and pregnancy complications United States Diabetes Mellitus Type 2 Female Metabolic syndrome business Body mass index Follow-Up Studies Polycystic Ovary Syndrome |
| Zdroj: | Can J Diabetes |
| Popis: | Polycystic ovary syndrome (PCOS) is a common reproductive/metabolic condition associated with obesity, type 2 diabetes (T2D) and depression in adult women. Depression in adults is related to PCOS dermatologic manifestations. Adolescents with obesity with or without T2D have elevated depression symptoms, but data from youth with PCOS and obesity with/without T2D are limited.Our study included girls, aged 11 to 17 years, with obesity and PCOS, PCOS+T2D or T2D, who were newly seen in an obesity complications clinic after March 2016. All participants had Center for Epidemiologic Studies-Depression (CES-D, 20 items) scores obtained within 6 months of PCOS or T2D diagnosis. Data on history of psychiatric diagnosis and treatment, metabolic syndrome and severity of acne and hirsutism were collected through chart review.One hundred five girls (47 with PCOS, 14 with PCOS+T2D, 44 with T2D) had similar age (15±1.8 years) and body mass index z scores (2.2±0.4). CES-D scores ≥16, indicating elevated depression symptoms, and CES-D scores ≥24, indicating severe depression symptoms, were observed in 60% and 30% of girls with PCOS, 78% and 71% of those with PCOS+T2D and 39% and 21% of those with T2D, respectively (p0.0001 for both cutpoints). A higher CES-D score was not associated with severity of hirsutism or acne (p0.05 for both).Adolescents with PCOS and obesity have higher rates of elevated depression symptoms compared with girls with T2D, which is not related to worse dermatologic symptoms. Because depression may impact both PCOS and T2D management and adherence to therapy, greater efforts should be made to screen for and address mental health in adolescents with PCOS and obesity, especially if T2D is present. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|