Life expectancy after aortic valve replacement in young patients
| Autor: | Manuel Carnero, Gertrudis Parody, Antonio García-Valentín, Emilio Monguió, Emiliano A. Rodríguez-Caulo, Alejandro Adsuar, Daniel Hernández-Vaquero, Juan Margarit, Andrea Ferreiro, Oscar Blanco-Herrera, Diego Macías, Elio Martín, Juan José Otero, Rafael Hernández-Estefanía, Elisabet Berastegui, Jacobo Silva, P. Pareja, José Antonio Blázquez, Miren Martín, Carlota Vigil-Escalera, Daniel Martinez, Delfina Fletcher-Sanfeliu, Ivana Pulitani, Souhayla Souaf, José A Corrales, Gregorio Laguna, Javier Arias-Dachary, Sergio Cánovas, Manel Castella, José F Valderrama |
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| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Aortic valve replacement Estenosis aórtica grave Exceso de mortalidad Excess mortality Reemplazo de válvula aórtica Severe aortic stenosis Population macromolecular substances Excess mortality 030204 cardiovascular system & hematology Transcatheter Aortic Valve Replacement 03 medical and health sciences Life Expectancy 0302 clinical medicine Aortic valve replacement Risk Factors medicine Humans education Aged Heart Valve Prosthesis Implantation education.field_of_study Relative survival Observed Survival Severe aortic stenosis business.industry Aortic Valve Stenosis General Medicine Middle Aged medicine.disease Surgery Stenosis Treatment Outcome Aortic Valve Heart Valve Prosthesis Baseline characteristics cardiovascular system Life expectancy business |
| Zdroj: | REVISTA ESPANOLA DE CARDIOLOGIA r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante instname Revista espanola de cardiologia (English ed.) r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe |
| ISSN: | 1885-5857 0300-8932 |
| Popis: | Introduction and objectives: In young patients with severe aortic stenosis, it is unknown whether their life expectancy restored after aortic valve replacement (AVR) is unknown. Methods: We analyzed all patients aged between 50 and 65 years who underwent isolated AVR in 27 Spanish centers during an 18-year period. We compared observed and expected survival at 15 years of follow-up. We repeated all analyses for patients without complications in the postoperative period. Results: A total of 5084 patients were analyzed. For the overall sample, observed survival at 10 and 15 years was 85.3% (95%CI, 84.1%-86.4%) and 73.7% (95%CI, 71.6%-75.6%), respectively. Expected survival was 90.1% and 82.1%. Cumulative relative survival for 1, 5, 10 and 15 years of follow-up was 97.4% (95%CI, 96.9%-97.9%), 96.5% (95%CI, 95.7%-97.3%), 94.7% (95%CI, 93.3%-95.9%), and 89.8% (95%CI, 87.3%-92.1%). For patients without complications, cumulative relative survival for 1, 5, 10 and 15 years was 100.3% (95%CI, 99.8%-100.5%), 98.9% (95%CI 97.6% -99.9%), 97.3% (95%CI, 94.9%-99.4%), and 91.9% (95%CI, 86.5%-96.8%). Conclusion: Life expectancy in young patients who have severe aortic stenosis and undergo AVR is lower than that of the general population. Life expectancy of individuals without complications during the postoperative period is also reduced. Therefore, baseline characteristics are likely the main factors that explain the reduction in life expectancy. (C) 2021 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved. |
| Databáze: | OpenAIRE |
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