Selective laser trabeculoplasty for early glaucoma: analysis of success predictors and adjusted laser outcomes based on the untreated fellow eye
| Autor: | Luis G. Biteli, Flavio Siqueira Santos Lopes, Mikael Chun, Carolina P. B. Gracitelli, Michele Ushida, Tiago S. Prata |
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| Rok vydání: | 2016 |
| Předmět: |
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medicine.medical_specialty Intraocular pressure Selective laser trabeculoplasty Open angle glaucoma genetic structures Glaucoma Ocular hypertension Trabeculectomy Cornea 03 medical and health sciences 0302 clinical medicine Interquartile range Predictive Value of Tests Ophthalmology Fellow eye medicine Humans Open-angle glaucoma Aged business.industry Age Factors General Medicine Early glaucoma Middle Aged medicine.disease eye diseases Treatment Regimen 030221 ophthalmology & optometry Regression Analysis Female sense organs Laser Therapy business 030217 neurology & neurosurgery Glaucoma Open-Angle Research Article |
| Zdroj: | BMC Ophthalmology |
| ISSN: | 1471-2415 |
| Popis: | Background To identify success predictors and to study the role of the fellow untreated eye as a co-variable for adjustment of intraocular pressure (IOP) outcomes following selective laser trabeculoplasty (SLT) in early open-angle glaucoma (OAG) patients. Methods A case series was carried out. Patients with uncontrolled early OAG or ocular hypertension (inadequate IOP control requiring additional treatment) underwent SLT (one single laser session) performed by the same surgeon in a standardized fashion. The same preoperative medical regimen was maintained during follow-up for all patients. Post-treatment assessments were scheduled at week 1 and months 1, 2, and 3. In order to account for possible influence of IOP fluctuation on laser outcomes, post-laser IOP values of the treated eye of each patient were also analyzed adjusting for IOP changes (between visits variation) of the untreated fellow eye (adjusted analysis). Pre and post-laser IOP values were compared using paired t-test. Factors associated with the magnitude of IOP reduction were investigated using multiple regression analysis. Results A total of 45 eyes of 45 patients were enrolled. Mean IOP was reduced from 20.8 ± 5.1 to 14.9 ± 2.9 mmHg at month 3 (p |
| Databáze: | OpenAIRE |
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