A 48-Hour Vegan Diet Challenge in Healthy Women and Men Induces a BRANCH-Chain Amino Acid Related, Health Associated, Metabolic Signature
| Autor: | François-Pierre Martin, Corinne Ammon Zufferey, Jim Kaput, Colleen Draper, Mingming Su, Wei Jia, Max Scherer, Irene Vassallo, Maurice Beaumont, Alessandro Di Cara, Nashmil Emami, Ornella Comminetti, Seu-Ping Guiraud, Laurence Guignard, Maya Shevlyakova, Jean-Philippe Godin, Cristiana Milone, Fabienne Praplan, Irina Monnard, Sofia Moco |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Diet Vegan medicine.medical_treatment Branched-chain amino acid Blood sugar Blood lipids Nutritional Status 030209 endocrinology & metabolism Biology Bile Acids and Salts 03 medical and health sciences chemistry.chemical_compound Eating 0302 clinical medicine Internal medicine medicine Humans chemistry.chemical_classification 030109 nutrition & dietetics Cholesterol Insulin Fatty Acids Vegan Diet Nutrients Lipids Healthy Volunteers Endocrinology chemistry Homeostatic model assessment Female Amino Acids Branched-Chain Blood Chemical Analysis Food Science Biotechnology Polyunsaturated fatty acid |
| Zdroj: | Molecular nutritionfood research. 62(3) |
| ISSN: | 1613-4133 |
| Popis: | cope : Research is limited on diet challenges to improve health. A short-term, vegan protein diet regimen nutritionally balanced in macronutrient composition compared to an omnivorous diet was hypothesized to improve metabolic measurements of blood sugar regulation, blood lipids, and amino acid metabolism. Methods and results : This randomized, cross-over, controlled vegan verses animal diet challenge was conducted on 21 (11 female,10 male) healthy participants. Fasting plasma was measured during a 3-day diet intervention for clinical biochemistry and metabonomics. Intervention diet plans met individual caloric needs. Meals were provided and supervised. Diet compliance was monitored. Conclusions : The vegan diet lowered triglycerides, insulin and homeostatic model assessment (HOMA-IR), bile acids, elevated magnesium levels, and changed branched-chain amino acids (BCAAs) metabolism (p |
| Databáze: | OpenAIRE |
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