Association between Periodontopathogens and CRP Levels in Patients with Periodontitis in Serbia

Autor: Pejcic, Ana, Kesic, Ljiljana, Milasin, Jelena, Brkic, Zlata, Mirkovic, Dimitrije
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal of Dental Research, Dental Clinics, Dental Prospects
Journal of Dental Research, Dental Clinics, Dental Prospects, Vol 5, Iss 1, Pp 10-16 (2011)
ISSN: 2008-2118
2008-210X
Popis: Background and aims. Recent epidemiological studies have shown that individuals with periodontitis have a significantly higher risk of developing coronary heart disease, which might be attributed to the complex microbiota in the dental plaque. Periodontopathogens have been reported as risk factors for cardiovascular disease. This study evaluated association of chronic periodontitis and periodontopathogens with CRP in systemically healthy Serbian adults. Materials and methods. Serum C-reactive protein levels were measured in 24 patients with moderate periodontitis, 26 patients with severe periodontitis, and 25 periodontally healthy subjects. Periodontal health indicators included gingival bleeding on probing and periodontal disease status. Patients with moderate periodontitis had low attachment loss and pocket depths of 5 mm. The control group with healthy gingiva had gingival sulcus of 5 mol/L was greater in the higher clinical AL group compared to the group with less attachment loss. Presence of periodontopathogens was also associated with elevated CRP levels and poor periodontal status. Conclusions. PD and subgingival periodontopathogens are associated with increased CRP levels. These findings suggest that periodontal infection may contribute to systemic inflammatory burden in otherwise healthy individuals.
Dental Research, Dental Clinics, Dental Prospects; ISSN 2008-210X
Databáze: OpenAIRE
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