Hormonal findings in association with abnormal corpus luteum function in the human: the luteal phase defect
| Autor: | Georgeanna Seegar Jones, Vernon Madrigal-Castro |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Adult
Ovulation endocrine system medicine.medical_specialty medicine.drug_class Biopsy Radioimmunoassay Anovulatory cycle Luteal phase Biology Body Temperature chemistry.chemical_compound Follicle-stimulating hormone Endometrium Corpus Luteum Internal medicine medicine Vaginal smear Humans Progesterone Vaginal Smears Chromatography Obstetrics and Gynecology Estrogens Luteinizing Hormone Endocrinology medicine.anatomical_structure Reproductive Medicine chemistry Estrogen Pregnanediol Female Follicle Stimulating Hormone Luteinizing hormone Corpus luteum Infertility Female Protein Binding |
| Zdroj: | Fertility and sterility. 21(1) |
| ISSN: | 0015-0282 |
| Popis: | An investigation of the ovarian-pituitary cycle in several patients with severe persistent luteal phase defects in an effort to understand the etiology in relation to the clinical symptomatology of the defect is reported. In conjunction with clinical hormonal evaluations basal body temperature vaginal smear pattern and endometrial biopsy these studies utilized radioimmunoassay for serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) urinary estrogen and pregnanediol assays and in 1 case serum progesterone assays. The results of the study indicated that at least 1 etiologic factor responsible for a luteal phase defect may be a poor cyclic LH stimulation. The aluteal cycle can be distinguished from the anovulatory cycle by the estrogen excretion pattern which may be normal by a detectable LH elevation at midcycle and probably by appreciable amounts of plasma progesterone. The anovulatory cycle studied had a fairly normal luteal span. The oligoluteal cycle studied had an apparently short luteal span of only 5 days as well as an abnormal steroidogenesis. The study of a patient with cyantoic heart disease illustrated the fact that abnormal steroidogenesis or corpus lutem function can be associated with peripheral factors. |
| Databáze: | OpenAIRE |
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