Oxidative stress does not influence weight loss induced by aerobic training in adults: randomized clinical trials
| Autor: | Mateus Duarte Ribeiro, Thiago de O Medeiros, Antônio E de Almeida, Raquel S Brito Silva, João Modesto Filho, Reabias de Andrade Pereira, Glêbia Alexa Cardoso, Ana Paula Urbano Ferreira, Alexandre Sérgio Silva, Yohanna de Oliveira, Bruno Rafael Virgínio de Sousa |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Physical Therapy Sports Therapy and Rehabilitation Walking 030204 cardiovascular system & hematology Overweight medicine.disease_cause Antioxidants Body Mass Index Running Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Weight loss Malondialdehyde Internal medicine Weight Loss medicine Humans Aerobic exercise Orthopedics and Sports Medicine Obesity Exercise Aerobic capacity business.industry Middle Aged Exercise Therapy Oxidative Stress 030104 developmental biology Endocrinology chemistry Body Composition Lean body mass Female Lipid Peroxidation medicine.symptom business Body mass index Oxidative stress |
| Zdroj: | The Journal of Sports Medicine and Physical Fitness. 60 |
| ISSN: | 1827-1928 0022-4707 |
| Popis: | Background High levels of oxidative stress promote degradation of the cell membrane impairing cellular function in fat oxidation. However, the influence of oxidative stress on exercise-induced weight-loss has not yet been investigated. Therefore, the aim of this study was to verify the influence of a lipidic peroxidation marker (malondialdehyde, MDA) and antioxidant status (total antioxidant capacity marker, TAC) on the magnitude of weight-loss by aerobic-induced exercise in previously sedentary overweight or obese individuals. Methods Seventy-five physically inactive adults were randomized into experimental (N.=58) and control (N.=17) groups, who engaged in a 12-week program of aerobic training walking and/or running (3 to 5 days/week) or stretching (1 day/week), respectively. Body composition (DXA), aerobic capacity (ergospirometric) and blood collections for oxidative stress analysis (MDA and TAC) were determined before and after the experimental protocol. Two-way ANOVA for repeated measures or Friedman's test were used to evaluate differences in time/group interaction. Pearson correlation was used to verify the relationship between the variables of oxidative stress and of body composition. Results Significant reduction was found in fat body mass of experimental when compared to control group (-1.3±1.9 kg versus -0.3±1.3, P=0.04). Experimental group also altered significantly the total body mass (-1.2±4.7 kg; effect size 0.44), body mass index - BMI (-0.3±1.1 effect size 0.37), fat percentage (1.3±1.6%; effect size 0.50) and lean body mass (0.6±1.5 kg; effect size 0.32).There was increase in MDA of 2.3 μmol/L to 2.7 μmol/L (P=0.00), without changes to TAC (25.6±13.9% to 28.0±10.4%). No correlation was found between these variations in body composition with either the initial values of MDA and TAC or delta variation of these indicators of oxidative stress in response to the training program. Conclusions Indicators of oxidative stress (MDA and TAC) does not influence the magnitude of weight-loss induced by aerobic training. |
| Databáze: | OpenAIRE |
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