The Effects of Ginseng Radix Rubra on Human Vascular Endothelial Cells

Autor: Yasuhiko Uchiyama, Eiichi Haruki, Kazuo Yoshida, Shigekatsu Nakajima, Hiromi Mizukawa
Rok vydání: 1998
Předmět:
Zdroj: The American Journal of Chinese Medicine. 26:365-373
ISSN: 1793-6853
0192-415X
DOI: 10.1142/s0192415x98000403
Popis: The effect of Ginseng Radix Rubra (Red ginseng) on human vascular endothelial cells was examined. Red ginseng was found to promote the proliferation of vascular endothelial cells, inhibit the production but promote the decomposition of endothelin, which is known to constrict blood vessels and raise blood pressure as well as accelerate the synthesis of nitric oxide. which is known to have an angio-tonic effect. Furthermore, Red ginseng was observed to increase the production of Interleukin 1ß, which is known to play important roles in the homeostatic activities of the human body such as immunity and inflammation as well as increasing the production of tissue plasminogen activators, which suppress the formation of thrombin in the blood coagulation and fibrinolysis mechanisms. It is suggested that Red ginseng has the effect of accelerating endothelial cells proliferation and of promoting physiological activities.
Databáze: OpenAIRE