Koinzidenz von Plattenepithelkarzinomen der Speiseröhre und Kopf-Hals-Karzinomen: Risiko und Früherkennung
| Autor: | P. Mir-Salim, Hans Scherübl, J. Steinberg, Ralf Kiesslich, U. Stoelzel, E. M. De Villiers, C. Schwertner |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Esophageal Neoplasm
medicine.medical_specialty Squamous cell cancer business.industry Head and neck cancer Gastroenterology Early detection medicine.disease Upper digestive tract digestive system diseases Survival benefit Field cancerisation Oncology Pharyngoscopy Internal medicine medicine business |
| Zdroj: | Zeitschrift für Gastroenterologie. 45:710-714 |
| ISSN: | 1439-7803 0044-2771 |
| DOI: | 10.1055/s-2007-963205 |
| Popis: | Patients suffering from head and neck cancer (HNC) have or will develop a second esophageal squamous cell cancer (ESCC) in 5 - 14 %. When a second esophageal neoplasm occurs in a HNC patient, the prognosis is generally determined by the ESCC, and unfortunately it is poor. Prospective clinical studies in Japan, Brazil, Taiwan, France and Germany have shown that screening or surveillance using Lugol chromoesophagoscopy enables early detection of second esophageal neoplasias. Such a surveillance results in a survival benefit for HNC patients. Vice versa, ESCC patients also have a risk of 9.3 - 11.4 % for a head and neck cancer. Periodic otolaryngeal examination and pharyngoscopy is recommended for curatively treated ESCC patients. Patients with a so-called field cancerisation of the airways and upper digestive tract thus require an interdisciplinary management and monitoring. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|