Glycemic Characteristics and Neonatal Outcomes of Women Treated for Mild Gestational Diabetes
Autor: | Patrick M. Catalano, Susan M. Ramin, Anthony Sciscione, Garland D. Anderson, Lisa Mele, Jorge E. Tolosa, George R. Saade, Dwight J. Rouse, Brian M. Casey, Catherine Y. Spong, Michael W. Varner, Yoram Sorokin, Celeste Durnwald |
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Rok vydání: | 2011 |
Předmět: |
Adult
Blood Glucose medicine.medical_specialty Adolescent Diet therapy Gestational Age Risk Assessment Severity of Illness Index Article Young Adult Abnormal oral glucose tolerance Pregnancy Internal medicine Diabetes mellitus Odds Ratio Humans Hypoglycemic Agents Insulin Medicine Glucose tolerance test C-Peptide medicine.diagnostic_test business.industry Neonatal hypoglycemia Pregnancy Outcome Obstetrics and Gynecology Fasting Glucose Tolerance Test Postprandial Period medicine.disease Gestational diabetes Diabetes Gestational Postprandial Glycemic index Endocrinology Glycemic Index Regression Analysis Female business |
Zdroj: | Obstetrics & Gynecology. 117:819-827 |
ISSN: | 0029-7844 |
DOI: | 10.1097/aog.0b013e31820fc6cf |
Popis: | To estimate the association between fasting and 2-hour postprandial blood glucose levels and neonatal outcomes in women treated for mild gestational diabetes. In this secondary analysis of a multicenter randomized treatment trial of mild gestational diabetes, the median fasting and 2-hour postprandial glucose levels were analyzed in 2-week intervals and change over time (slope) was calculated for women with gestational diabetes (abnormal oral glucose tolerance test) and a fasting glucose less than 95 mg/dL who received nutritional management with self blood glucose monitoring and insulin as needed. Regression analyses were performed to estimate the relationship between median fasting and postprandial glucose and neonatal fat mass, cord blood C-peptide, birth weight, large-for-gestational-age neonates, macrosomia (greater than 4,000 g), and neonatal hypoglycemia. Among 460 women with gestational diabetes, median fasting (P |
Databáze: | OpenAIRE |
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