The A, B and H Blood-Group Antigens in Human Placenta
| Autor: | Aron E. Szulman |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Isoantigens
Endothelium Embryo/fetus Placenta Extraembryonic Membranes Fluorescent Antibody Technique Gestational Age Biology Umbilical cord Antibodies Epithelium ABO Blood-Group System Umbilical Cord Fetus Antigen Pregnancy ABO blood group system medicine Humans reproductive and urinary physiology Immune Sera Trophoblast General Medicine Capillaries Trophoblasts Histocompatibility medicine.anatomical_structure embryonic structures Immunology Blood Group Antigens Female |
| Zdroj: | New England Journal of Medicine. 286:1028-1031 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm197205112861904 |
| Popis: | Thirty human placentas of embryo fetuses of various ABO blood groups and representing all stages of pregnancy between the fifth week (ovulation age) and term were examined for the ABH antigens by immunofluorescence. The trophoblast was consistently negative for both the H and A, B antigens, and the endothelium of the vessels of the chorion, villi and umbilical cord possessed only the basic H structure. The findings contrast with full antigenic complement of the endothelium and of sundry epithelia in the embryo fetus proper, each according to its ABO blood group. The lack of demonstrable ABH antigens in the trophoblast tallies with a similar lack of demonstrable transplantation antigens; it renders the trophoblast unassailable by maternal A, B isoagglutinins. |
| Databáze: | OpenAIRE |
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