Pharmacokinetic, pharmacodynamic, and clinical aspects of ovulation induction agents: A review of the literature
| Autor: | Serkan Kahyaoglu, Ahmet Zeki Işık, Bulent Yilmaz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Infertility
medicine.medical_treatment media_common.quotation_subject Ovarian hyperstimulation syndrome lcsh:Medicine Review Controlled ovarian hyperstimulation Bioinformatics 030226 pharmacology & pharmacy lcsh:Gynecology and obstetrics 03 medical and health sciences 0302 clinical medicine Follicular phase medicine Milestone (project management) pharmacokinetic Ovulation lcsh:RG1-991 media_common 030219 obstetrics & reproductive medicine Reproductive Technique business.industry lcsh:R Obstetrics and Gynecology medicine.disease pharmacodynamic Ovulation induction ovulation induction business infertility |
| Zdroj: | Journal of the Turkish-German Gynecological Association, Vol 18, Iss 1, Pp 48-55 (2017) Journal of the Turkish German Gynecological Association |
| ISSN: | 1309-0380 1309-0399 |
| Popis: | Controlled ovarian hyperstimulation is a key step for successful outcomes of assisted reproductive technique cycle outcomes. Many medications are available, which are commonly useed solely or in combination to achieve multiple follicular development. Pharmacokinetic, pharmacodynamic, and clinical information of ovulation induction drugs deserve to be elucidated for every individual patient before commencing infertility treatment. New concepts and new treatment protocols are introduced as ovulation physiology is understood by infertility specialists. Increasing treatment success by minimizing aderse effects is a milestone of all ovarian stimulation protocols that use these novel interventions. Achievement of a satisfactory cycle outcome includes retrieval of sufficient oocytes, a single clinical pregnancy, and avoidance of ovarian hyperstimulation syndrome. In this review, we evaluate the current literature to determine the most reliable and relevant information about the most used ovulation induction drugs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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