Long-term effects of sulfur mustard on civilians' mental health 20 years after exposure (The Sardasht-Iran Cohort Study)
| Autor: | Ali Montazeri, Mohammad Mehdi Naghizadeh, Rasoul Roshan, Tooba Ghazanfari, Zeinab Ghazanfari, Mahdiyeh Melyani, Mohammad Reza Soroush, Azadeh Tavoli, Parvin Rahnama |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Digestive System Diseases Hostility Iran Cohort Studies Psychoticism Environmental health Mustard Gas Medicine Humans Chemical Warfare Agents Somatoform Disorders Iraq War 2003-2011 Afghan Campaign 2001 business.industry Mental Disorders Research Public Health Environmental and Occupational Health General Medicine Environmental exposure Environmental Exposure Middle Aged medicine.disease Mental health Control Groups Checklist Distress Socioeconomic Factors Quality of Life Anxiety Female medicine.symptom business Somatization Clinical psychology Cohort study |
| Zdroj: | Health and Quality of Life Outcomes |
| ISSN: | 1477-7525 |
| Popis: | Background Sulfur mustard (SM) is an alkylating agent that induces short and long term toxicity on various organs. The aim of this study was to assess the long-term psychological symptoms among samples of exposed to sulfur mustard gas compared with unexposed civilians 20 years after exposure. Methods This historical cohort study was conducted on 495 civilians of Sardasht and Rabat in two age matched groups, including 367 sulfur mustard exposed participants from Sardasht and 128 unexposed subjects from Rabat. Psychological symptoms was assessed using the Symptom Check List-90 Revised (SCL-90-R) including measures of somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, and psychoticism providing three global distress indices namely: Global Severity Index (GSI), Positive Symptom Total (PST) and Positive Symptom Distress Index (PSDI). Comparison was made between exposed and unexposed civilians. Results There were significant differences in somatization (P = 0.002), obsessive-compulsive (P = 0.031), depression (P = 0.007), anxiety (P = 0.042), and hostility (P = 0.002), between the exposed and unexposed groups. In addition there were significant differences between two groups concerning the GSI (P = 0.045) and the PSDI (P Conclusions The findings from this study showed that civilians who exposed to sulfur mustard gas were suffering from a number of psychological symptoms even 20 years after exposure. Providing mental health services and more resource allocation for this community are highly recommended. |
| Databáze: | OpenAIRE |
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