Randomized clinical trials of patients with acute myocardial infarction-related cardiogenic shock:A systematic review of used cardiogenic shock definitions and outcomes
| Autor: | Johannes Grand, Christian Hassager, Martin Frydland, Jakob Josiassen, Jacob E. Møller, Anders Perner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Shock Cardiogenic/etiology medicine.medical_treatment Cardiac index Myocardial Infarction Shock Cardiogenic Acute myocardial infarction Targeted temperature management law.invention Percutaneous Coronary Intervention Randomized controlled trial law Internal medicine medicine Humans Myocardial infarction Cardiogenic shock Randomized Controlled Trials as Topic Ejection fraction business.industry Myocardial Infarction/complications Percutaneous coronary intervention Acute heart failure medicine.disease Cardiac arrest Blood pressure Treatment Outcome Cardiology Heart-Assist Devices Cardiology and Cardiovascular Medicine business |
| Zdroj: | Josiassen, J, Frydland, M, Hassager, C, Møller, J E, Perner, A & Grand, J 2021, ' Randomized clinical trials of patients with acute myocardial infarction-related cardiogenic shock : A systematic review of used cardiogenic shock definitions and outcomes ', Kardiologia Polska, vol. 79, no. 9, pp. 1003-1015 . https://doi.org/10.33963/KP.A2021.0072 |
| DOI: | 10.33963/KP.A2021.0072 |
| Popis: | Background: Cardiogenic shock (CS) is a critical complication to acute myocardial infarction (AMI), with short-term mortality rates exceeding 40%. However, no international consensus of a CS definition exists. This may compromise interstudy comparability. Aims: The aim of the current study was to review differences and similarities of CS enrolment criteria in AMI-related CS randomized clinical trials (RCT). Methods: From the electronic databases MEDLINE and EMBASE we identified all AMI-related CS trials. Results: A total of 19 trials comprising a total of 2674 unique patients with CS were identified. Seven trials investigated left ventricular assist devices, eight investigated medical treatments, three percutaneous coronary intervention (PCI), and one trial investigated targeted temperature management. The inclusion criteria, baseline hemodynamics, endpoints, and mortality varied markedly between trials. Hypotension was the most frequent overall inclusion criterion (17 [90%] trials), and a systolic blood pressure |
| Databáze: | OpenAIRE |
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