Hexafluoroisopropanol: a powerful solvent for the hydrogenation of indole derivatives. Selective access to tetrahydroindoles or cis-fused octahydroindoles

Autor:	Bernard Fenet, Fabienne Fache, Damien Clarisse
Rok vydání:	2012
Předmět:	Solvent Indole test Chemistry Organic Chemistry Organic chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organicbiomolecular chemistry. 10(32)
ISSN:	1477-0539
Popis:	Pd/C in HFIP was used to hydrogenate indole derivatives under relatively mild conditions, leading to potential synthetic intermediates of bioactive compounds. Depending on their substitution, tetrahydroindoles or octahydroindoles could selectively be obtained.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca68bbfa988fba48c9db1be795f9561d https://pubmed.ncbi.nlm.nih.gov/22782846 Zobrazit plný text záznamu