Nitrazepam: lastingly effective but trouble on withdrawal
| Autor: | Vlasta Brezinova, W M Hunter, Liisi Adamson, Kirstine Adam |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Drug Nitrazepam media_common.quotation_subject Sleep REM Growth hormone medicine Humans General Environmental Science media_common business.industry General Engineering General Medicine Middle Aged Sleep in non-human animals Substance Withdrawal Syndrome Nitrazepam 5 MG Growth Hormone Anesthesia General Earth and Planetary Sciences Female Sleep Stages Sleep business Research Article medicine.drug |
| Zdroj: | BMJ. 1:1558-1560 |
| ISSN: | 1468-5833 0959-8138 |
| DOI: | 10.1136/bmj.1.6025.1558 |
| Popis: | The sleep of 10 volunteers with an average age of 57 years was recorded electrophysiologically before, during, and after nitrazepam 5 mg nightly for 10 weeks. Sleep was longer and less broken on the drug and no tolerance was obvious after two months' use. Withdrawal of the drug, however, caused sleep to be temporarily worse than before the drug had been taken. Slow-wave sleep was reduced by nitrazepam, but the accompanying secretion of growth hormone was not impaired. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|