Psychometric validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24)
| Autor: | Greimel, E., Nordin, A., Lanceley, A., Creutzberg, C.L., Poll-Franse, L.V. van de, Radisic, V.B., Galalae, R., Schmalz, C., Barlow, E., Jensen, P.T., Waldenstrom, A.C., Bergmark, K., Chie, W.C., Kuljanic, K., Costantini, A., Singer, S., Koensgen, D., Menon, U., Daghofer, F., EORTC Quality Life Grp |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Questionnaires Cancer Research medicine.medical_specialty Psychometrics medicine.medical_treatment Sensitivity and Specificity Quality of life Endometrial cancer Questionnaire development EORTC Psychometric properties mrc astec radiotherapy health trial irradiation survivors Cronbach's alpha Quality of life Surveys and Questionnaires medicine Humans Karnofsky Performance Status Aged Gynecology Aged 80 and over business.industry Endometrial cancer Discriminant validity Cancer Reproducibility of Results social sciences Middle Aged medicine.disease humanities Endometrial Neoplasms Radiation therapy Clinical trial Oncology Socioeconomic Factors Patient Satisfaction Physical therapy Quality of Life Female business |
| Zdroj: | Greimel, E, Nordin, A, Lanceley, A, Creutzberg, C L, van de Poll-Franse, L V, Radisic, V B, Galalae, R, Schmalz, C, Barlow, E, Jensen, P T, Waldenström, A-C, Bergmark, K, Chie, W-C, Kuljanic, K, Costantini, A, Singer, S, Koensgen, D, Menon, U, Daghofer, F & EORTC Quality of Life Group 2011, ' Psychometric validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24) ', European Journal of Cancer, vol. 47, no. 2, pp. 183-90 . https://doi.org/10.1016/j.ejca.2010.08.014 European Journal of Cancer, 47(2), 183-190 |
| Popis: | Aim: A validation study was conducted to evaluate the psychometric properties of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24). This module was designed to assess disease and treatment specific aspects of the quality of life (QoL) of patients with endometrial cancer. Methods: Two hundred and sixty-eight women with endometrial cancer were recruited in different phases of treatment: after pelvic surgery (Group 1); during adjuvant chemotherapy and/or radiotherapy (Group 2); after completion of treatment (Group 3). Patients completed the EORTC QLQ-C30, the endometrial cancer module and a short debriefing questionnaire. Results: Multi-trait scaling analyses confirmed the hypothesised scale structure of the QLQ-EN24. Internal consistency reliability was good with Cronbach's alpha coefficients ranging from 0.74 to 0.86 (lymphoedema 0.80, urological symptoms 0.75, gastrointestinal symptoms 0.74, body image problems 0.86 and sexual/vaginal problems 0.86). Convergent and discriminant validity did not show any scaling errors for the subscales. The QLQ-EN24 module discriminated well between clinically different groups of patients. All items exhibited a high completion rate with less than 2% missing values except for the sexuality items (19%). Conclusion: The validation study supports the reliability, the convergent and divergent validity of the EORTC QLQ-EN24. This newly developed QLQ-EN24 module is a useful instrument for the assessment of the QoL in patients treated for endometrial cancer in clinical trials. (C) 2010 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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