A Multisite, Randomized Controlled Clinical Trial of Computerized Cognitive Remediation Therapy for Schizophrenia
| Autor: | Edith Pomarol-Clotet, Andrea Lazcanoiturburu, Celia Mareca, Josep Tristany, Cristina de Pablo Mozo, María Jañez-Álvarez, Ana M. Donaire, Cristina Teixido, María R. Ovejero, Mónica Pérez-Hernández, Ana Llorente, Eduardo García-Laredo, Jesus J. Gomar, E. Valls, Francisco del Olmo, Francisco J. de Álvaro, Peter J. McKenna, Luis Granell, Joaquim Radua, Carlos Rebolleda-Gil, Ana Moreno-Alcázar |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
cognition
Adult Male medicine.medical_specialty medicine.medical_treatment neuropsychology Executive Function Young Adult Physical medicine and rehabilitation Intervention (counseling) medicine Humans Treatment Failure Young adult Aged Memory Disorders Cognitive Behavioral Therapy Neuropsychology Cognition Regular Article Middle Aged medicine.disease Clinical trial schizophrenia Psychiatry and Mental health Cognitive remediation therapy Schizophrenia Therapy Computer-Assisted Cognitive therapy cognitive remediation Female Psychology Cognition Disorders Clinical psychology |
| Zdroj: | Schizophrenia Bulletin |
| ISSN: | 1745-1701 0586-7614 |
| Popis: | The effectiveness of cognitive remediation therapy (CRT) for the neuropsychological deficits seen in schizophrenia is supported by meta-analysis. However, a recent methodologically rigorous trial had negative findings. In this study, 130 chronic schizophrenic patients were randomly assigned to computerized CRT, an active computerized control condition (CC) or treatment as usual (TAU). Primary outcome measures were 2 ecologically valid batteries of executive function and memory, rated under blind conditions; other executive and memory tests and a measure of overall cognitive function were also employed. Carer ratings of executive and memory failures in daily life were obtained before and after treatment. Computerized CRT was found to produce improvement on the training tasks, but this did not transfer to gains on the primary outcome measures and most other neuropsychological tests in comparison to either CC or TAU conditions. Nor did the intervention result in benefits on carer ratings of daily life cognitive failures. According to this study, computerized CRT is not effective in schizophrenia. The use of both active and passive CCs suggests that nature of the control group is not an important factor influencing results. |
| Databáze: | OpenAIRE |
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